Initiatives to institute environmental and policy change in communities, to reduce obesity and promote active living, call for the participation of multiple stakeholder groups. These initiatives not only require collaboration across disciplines, but across cultural communities as well. Building relationships is important, but what factors are key in determining the success of a collaborative effort? Participants explored promising practices for building healthier communities through cross-sector collaboration, learned about 20 evidence-based factors that, when present, can increase a group’s likelihood of attaining shared goals, and engaged in hands-on exercises to assess their own collaborative initiatives (both those existing and under consideration). This workshop was aimed at improving collaborative knowledge and skills among public health and community development practitioners at all experience levels.